Mebendazole Totally Explained

Everything about Mebendazole totally explained

This article is about a pharmaceutical drug, for the automobile brand abbreviated as MBZ, see Mercedes-Benz Mebendazole or MBZ, marketed as Ovex, Vermox, Antiox or Pripsen, is a benzimidazole drug that's used to treat infestations by worms including pinworms, roundworms, tapeworms, hookworms, and whipworms. The active ingredient in Pripsen powder is piperazine.

Mechanism

Mebendazole (C₁₆H₁₃N₃O₃) causes slow immobilization and death of the worms by selectively and irreversibly blocking uptake of glucose and other nutrients in susceptible adult intestine where helminths dwell. It is a spindle poison that induces chromosome nondisjunction.

Dosage

Oral dosage is 100 mg every 12 hours for 3 days, although sometimes the dosage is just one 500 mg dose, followed by another dose two weeks later if the infection hasn't cleared up. The dosage may differ depending on which type of worm someone is infected with.

Further Information

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